Release date: 2018-04-10
Recently, the Anhui Stem Cell Society announced that the cells of Peking University’s “Frozen Frozen Disease†female doctoral sputum have been “reprogrammed†by researchers to induce pluripotent stem cells (iPSC), which will be promoted through further research. Early diagnosis and "precise" treatment of frozen disease.
On March 4, 2018, the famous British physicist Stephen Hawking died. Hawking was diagnosed with amyotrophic lateral sclerosis (ALS) at the age of 21, which is a neurological disease. Injury to the upper motor and lower motor neurons causes the patient to gradually appear and aggravate muscle weakness, muscle atrophy, difficulty swallowing, drinking water coughing and unclear speech, accompanied by muscle beating, check the body to find symptoms such as increased sputum reflexes) , also known as the "freezing people."
Peking University female doctor was diagnosed with suspected motor neuron disease in January 2016 and died in January 2018. She had made a decision to donate her body after death. Unfortunately, her organ was not eligible for donation. The last wish was not fulfilled. However, although he failed to donate organs, he handed over his cells to the Anhui Provincial Stem Cell Society and the China University of Science and Technology-Zhongsheng Trace Cell Medicine Joint Laboratory on October 19 last year to help the early days. To overcome the worldwide problem of gradual freezing, to save the lives of more patients with gradual freezing.
Through several years of research, the laboratory has "reprogrammed" Dr. Yu's cells into induced pluripotent stem cells (iPSCs) similar to embryonic stem cells.
It is reported that the next step will be to cooperate with domestic stem cell and regenerative medicine research institutes to differentiate her iPSC into motor neurons and use it for pathological research and drug screening to promote early diagnosis and "precise" treatment of gradual freezing. .
Freezing disease "iPSC schematic, for researchers
Professor Liu Wei of Nanjing Medical University, who has been engaged in the differentiation of iPSC nerves, said that by dividing the iPSC into a motor neuron in a culture dish, we can directly observe and study the mechanism and progress of the occurrence of gradual freezing, which will be for us. It is hoped that the Chinese people will overcome the difficulties of freezing. In fact, this research method has precedents in the world. In 2014, the Clifford Woolf team at Boston Children's Hospital and Harvard University's Stem Cell Institute differentiated iPSCs derived from patients with specific genetic mutations into motoneurons, and used these neurons to screen out the relevant channel activator Retigabine. Inhibition of excessive excitability of these motor neurons increases the survival rate of neurons. Based on the results of this study, the US FDA quickly opened the green channel and reviewed and approved Retigabine for clinical treatment of patients with progressive genetic disease with similar genetic background in less than one year.
Dr. Yu Junying, one of the chief scientists of Zhongsheng Trace Source and one of the inventors of human iPSC technology, believes that due to the scarcity of patients' living cells, the development and testing of drugs worldwide relies mainly on animal experiments and cancer cell lines. These research tools and human body under physiological conditions Cellular differences lead to high failure rates in the development of new drugs during clinical trials. The iPSC cell bank of the Chinese population can be constructed by using the cells of the patient carrying various rare genetic diseases and reprogramming into iPSC cell lines of various specific diseases in vitro. Then use these diseases iPSC to establish a disease cell model in the culture dish, which can more intuitively and accurately reflect the pathological mechanism of the disease, and provide a powerful tool for developing new therapeutic drugs and effective treatment plans.
Source: Zhongxinwang Medical Valley Comprehensive
Dehydrated Purple Sweet Potato Powder
food grade tomato powder has high nutritional value, low calorie, antioxidant, anti-cancer; it can remove freckles, beauty, anti-aging and weight loss. Dehydrated Tomato Powder is suitable for both internal and external use. It has a "beautiful" feature. Suitable for low-fat menu, slimming beauty. It is worth mentioning that tomatoes contain lycopene, and lycopene is a powerful antioxidant that helps delay aging, and also fights stress and cancer. And can balance water and oil secretion. Tomato powder is slightly modified to make different facial masks such as cleansing, repairing, freckle removal, and whitening. The new crop tomato powder is sweet, sour and slightly cold. It has the functions of promoting body fluid and quenching thirst, strengthening the stomach and digesting food, cooling blood and calming the liver, clearing away heat and detoxifying, and lowering blood pressure. patience.
Dehydrated Purple Sweet Potato Powder,Delicacy Purple Sweet Potato Powder,Organic Nutrition Purple Sweet Potato Powder,Organic Purple Sweet Potato Extract Powder
Laian Xinshuyu Food Co., Ltd , https://www.xinshuyufood.com