Japanese scholar mouse experiments found genes that determine the position of the animal's head

How is the position of the head of a mammal from the development of a fertilized egg to an embryo? The Japanese scholars discovered the principle through mouse experiments in early March 2004, which is helpful for the use of fertilized eggs and other organs and tissues for regenerative medicine. Professor Hamadabosaku of the Graduate School of Osaka University in Japan who participated in the study said on March 9 that through the study of the embryonic process of fertilization of mouse fertilized eggs, people now only know that the egg will produce DVE cells after more than 5 days of fertilization. Developed into the head, DVE cells are initially located at the top of the embryo and then move to one side and eventually settle in a certain place to grow. The team led by Prof. Hamada has newly discovered two genes that drive the movement of DVE cells. These two genes are LEFTY1 and CERL. They inhibit cell division in the direction of movement of DVE cells, while cell division continues in other directions, so that DVE cells pushed by the proliferating cell population can only move in the direction in which cell division is inhibited, and finally settle at a certain position. . According to Professor Hamada, these two genes also play an important role in determining the body's control. This result has been published in the British "Nature" magazine published on March 4.

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