- Model NO.: CAS No: 120511-73-1
- Assay: 99%
- Minimum Order Quantity: 10g
- Payment Options: Western Union, Moneygram, Bank Transfer
- Transport Package: Professional Packaging Team
- Origin: China
- CAS: 120511-73-1
- Appearance: White Powder
- Shipping Leading Time: Within 24 Hours After Receiving The Payment
- Trademark: Pharmade
- Specification: SGS, ISO, GMP
Quick Details:
Arimidex
CAS No:120511-73-1
Molecular formula:120511-73-1
Molecular weight:293.37
Appearance:White powder.
Assay:99%
Delivery time:5-7 business days door-to-door
Minimum order:50g
Supply ability:40kg/month
Quality standard:USP30
Usage: Arimidexis an aromatase-inhibiting drug approved for treatment of breast cancer after surgery, as well as for metastasis in both pre and postmenopausal women. The severity of breast cancer is increased by estrogen, as sexhormones cause hyperplasia, and differentiation at estrogen receptor sites. Arimidexworks by inhibiting the synthesis of estrogen.
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Description :
Arimidexis used to treat certain types of breast cancer in women who have already stopped menstruating (postmenopausal). It is also used for women who have already had other cancer treatments
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Many breast cancer tumors grow in response to estrogen. This medicine interferes with the production of estrogen in the body. As a result, the amount of estrogen that the tumor is exposed to is reduced, limiting the growth of the tumor.
Specification :
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| Items | Standard | Results |
| Description | White crystalline powder | Complies |
| Identification | IR HPLC Reactive |
Conform with standard IR Conform with standard HPLC Conform |
| Solubility | Freely soluble in methanol,acetone, ethanol and tetrahydrofuran. And very soluble in acetonitrile |
Complies |
| Total Impurity | max.0.5% | 0.18% |
| Total Unspecified Impurity | max. 0.2% | 0.08% |
| Individual unspecified impurlty | max. 0.1% | 0.05% |
| Related compound B | max. 0.2% | 0.07% |
| Related compound C | max. 0.2% | 0.04% |
| Related compound D | max. 0.1% | 0.05% |
| Related compound E | max. 0.1% | 0.06% |
| Limit of cyclohexane | max. 0.08% | ND |
| Limit of ethylacetate | max. 0.1% | 0.07% |
| Melting point | 81.0~84.0ºC | 82.5~83.2ºC |
| Water | max. 0.3% | 0.21% |
| Residue on ignition | max. 0.1% | 0.07% |
| Heavy Metals | max.0.001% | Complies |
| Assay(HPLC) | 98.0%~102.0% | 99.8% |
| Storage | Cool and dry | |
| Conclusion | It complies to USP32Â | |
Applications :
Hormones are chemical substances that are produced by glands in the body, which enter the bloodstream and cause effects in other tissues.  For example, the hormone made in the testicles and is responsible for male characteristics such as deepening voice and increased body hair.  The use of hormone therapy to treat cancer is based on the observation that receptors for specific hormones that are needed for cell growth are on the surface of some tumor cells. Â
Hormone therapies work by stopping the production of a certain hormone, blocking hormone receptors, or substituting chemically similar agents for the active hormone, which cannot be used by the tumor cell.  The different types of hormone therapies are categorized by their function and/or the type of hormone that is effected.
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Anastozole is an aromatase inhibitor.  This means it blocks the enzyme aromatase (found in the body's muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink.
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